The library
All articles from Longevity Science Daily
41 articles
93 people, average age 60, joined a juggling study. Only some learned it, and their brains grew. Three months after they stopped, their brains went back.
Send one DNA sample to the lab twice and the leading clocks disagree with themselves by up to 8.6 years. No intervention has ever moved them that far.
PEARL pre-registered visceral fat as its primary outcome. It came back at p = 0.942. Nearly everything quoted as a PEARL finding came from elsewhere in the paper.
Women outlive men almost everywhere. Among nuns and monks living alike, the gap is under a year. The rest is not biology, and the extra years are not healthy.
The bone and lipid changes are measured and sharp. The epigenetic clock claim is not: no study has run one on the same women before and after menopause.
Canagliflozin added 14 percent to median lifespan in male mice. Females got three times more drug in their blood and no benefit at all.
Statins block the pathway that makes CoQ10. That part is true, and it is why the supplement exists. It is also not why your muscles hurt.
Only about 40 percent of people carry the gut bacteria that make urolithin A. Trials found about a 12 percent gain in leg strength, and several missed their main goal.
Mice on a low-methionine diet eat freely, sometimes more than normal, and still live longer. The closest thing to caloric restriction without the calorie counting.
Good insulin sensitivity is treated as a sign you will age well. New 2026 animal work, and a closer look at the human data, shows the link is looser than the slogans suggest.
A 2023 taurine study extended mouse lifespan by about 10 percent. Its human half was a correlation, not a trial. Two 2025 studies found taurine does not fall with age.
Researchers gathered brain scans from 18,701 people in 34 countries. Where the air, the housing and the inequality were worse, the brains looked older.
For fifty years we've trusted omega-3 to slow aging. On aging, the evidence is thinner than its reputation: the big one-gram heart trials mostly came back empty.
Spermidine is a compound in food that switches on cellular cleanup. It extends life in animals and tracks with lower mortality in people. The trials are smaller than the hype.
Both raise NAD+. They take different routes to get there, and the human evidence behind each one is not the same. Here is how to choose.
Fisetin is a plant flavonoid sold as a senolytic supplement. In old mice it improves artery function by clearing senescent cells. The human evidence is not in yet.
Neurons survive by recycling. When that cleanup fails, Alzheimer's accelerates. Restoring it may slow disease in ways amyloid drugs cannot.
Rapamycin extends lifespan in every species tested. Whether humans should take it off-label for longevity is a question the data has not yet answered.
Senescent cells stop dividing but refuse to die. They accumulate with age, leak inflammatory signals, and may be one of the most targetable drivers of aging.
Your mitochondria slow down with age. Exercise is the proven fix. The supplement shelf is a different story, and the honest picture is more interesting.
We added two decades to human life last century. About ten of those years are spent sick. The gap between living longer and living well is the real longevity problem.
NAD+ supplements raise blood levels. What they do beyond that, and whether healthy people should take them, is a much harder question.
Up to 40% of weight lost on the strongest GLP-1 drugs is muscle and bone, not fat. About two thirds of that weight comes back within a year of stopping.
Researchers studied 186 pairs of identical twins. The twin who got more sun looked older. Same genes, same age, different skin.
Cortisol is the most vilified hormone in wellness. It's also the reason you wake up, survive surgery, and think under pressure.
A 1968 study kept young men in bed for three weeks. They lost 27% of their VO2 Max. Three weeks did more to their fitness than the next thirty years.
Hearing aids slowed cognitive decline by 48% in older adults already at higher risk of it. Hearing loss is the biggest dementia risk you can change.
Women experience adverse drug effects at twice the rate of men. 7 of 10 longevity drugs work better in males. The science has a blind spot.
Social isolation increases mortality risk by 29-50%, rivaling smoking. How relationships affect inflammation, brain health, and biological aging.
In deep sleep, the space between your brain cells opens up by about 60%. Fluid runs through and washes out the day's waste, including Alzheimer's proteins.
The science behind cardiorespiratory fitness as the strongest predictor of lifespan - and why the humble 'easy run' might matter more than you think.
Your lungs hold about 480 million tiny air sacs. Oxygen crosses there into your blood, your heart moves it, and your muscles use it.
A fasting glucose of 99 comes back normal. So does 80, and the risk is not the same. The normal range is drawn around 95 out of 100 people the lab tested.
Adults in a two year trial aimed to cut a quarter of their calories. They managed about 12 percent. Even that slowed their pace of aging by 2 to 3 percent.
About 35% of American adults have metabolic syndrome. Among adults 60 and older, it's more than half. You can be thin and still have it.
Several thousand older Poles were studied. Among those aging well, 2.9% of the least inflamed died within three years. Of the most inflamed, 25.3% did.
Over 1,200 older people at risk of dementia were split in two. Half got exercise, diet, brain training, company and heart checks. Their thinking improved 25% more.
In 2004, researchers measured cell aging in mothers, some caring for a sick child. The most stressed had cells at least ten years older than the calmest.
In the places where people live longest, about 95% of the calories come from plants. Beans are a staple. Meat is mostly for special occasions.
More than 150 human trials have tested resveratrol. Most found nothing. No supplement has been shown to make a person live longer.
In 2013 a team of researchers listed nine things that go wrong as the body ages. Ten years later they added three more. Exercise hits seven of the twelve.